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The rate of weight regain A 2025 narrative review in the Journal of Clinical Medicine examined weight regain trajectories across multiple GLP-1 receptor agonist studies
After prolonged HFD feeding, mice exhibited progressive weight gain and increased adiposity, accompanied by significantly reduced grip strength, diminished skeletal muscle fiber cross-sectional area, and marked reductions in muscle mass compared to standard diet-fed controls
Godley, B
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The novel dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP-1) receptor agonist Tirzepatide transiently delays gastric emptying similarly to selective long-acting GLP-1 receptor agonists
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